Dose (biochemistry)

Factors affecting dose

  • Concentration of the agent being administered
  • Duration of exposure to the agent
  • Route of administration
  • Metabolic effects illustrated by dose-response curves
  • Impact of drug or supplement function on dosing

Medicines

  • Over-the-counter medications
  • Dosage based on age
  • Risk of under or overdosing due to variation in body weight
  • Instructions for repeated small doses if symptoms persist
  • Prescription drugs
  • Dosage based on body weight
  • Calculation of safe one-time dose or multiple doses per day
  • Medication underdosing due to failure to adjust dosage as needed
  • Medical cannabis
  • Dosage dependent on individual reaction and condition being treated
  • Recommended CBD to THC ratios for different ailments
  • Continual adjustment of dosing to find the right balance

Cancer

  • Calculation of drug dosages based on body surface area
  • Inexactness of available formulae for measuring body surface area
  • Toxicity-adjusting dosing to monitor immune suppression
  • Challenges in selecting the best dosing method for individual patients
  • Ongoing research for safer and more accurate dosing methods

Ongoing research

  • Investigation of dosing on a molecular level
  • Conventional delivery systems, nanoparticle delivery, light-triggered delivery, etc.
  • Monitoring drug particles in the blood for individualized dosing
  • Electrochemical aptamer-based sensing for detecting drug concentration
  • Success of detecting trace amounts of cocaine in blood using microfluidic detection system

Cleanup and quality standards

  • Need for cleanup to meet Wikipedia's quality standards
  • Excessive waffle and vagueness in the article
  • Importance of trimming down to relevant information
  • Call for improvement from readers to help enhance the article
  • Date of cleanup request: April 2019

Vaccine administration

  • Different vaccines require different doses.
  • The dose of a vaccine depends on factors such as age and health condition.
  • The dose is determined by healthcare professionals.
  • Administering the correct dose is crucial for vaccine efficacy.
  • Vaccines are usually given in multiple doses to ensure effectiveness.

Nutrient recommendations

  • Dietary Reference Intakes (DRI) provide guidelines for nutrient intake.
  • DRIs are developed by the Office of Dietary Supplements.
  • DRIs vary depending on age, gender, and life stage.
  • Adequate nutrient intake is essential for overall health.
  • Nutrient deficiencies can lead to various health problems.

Calcium intake

  • The Institute of Medicine sets Dietary Reference Intakes for calcium.
  • Adequate calcium intake is necessary for strong bones and teeth.
  • Calcium requirements vary based on age and gender.
  • Calcium-rich foods include dairy products, leafy greens, and fortified foods.
  • Calcium supplements may be recommended for individuals with low intake.

Vitamin D intake

  • The Institute of Medicine sets Dietary Reference Intakes for vitamin D.
  • Vitamin D is essential for bone health and immune function.
  • Sun exposure is a natural source of vitamin D.
  • Vitamin D requirements vary based on age and life stage.
  • Vitamin D deficiency is common, especially in certain populations.

Multivitamin/mineral supplements

  • Multivitamin/mineral supplements provide a combination of essential nutrients.
  • They are intended to complement a balanced diet.
  • Supplements should not replace a healthy eating pattern.
  • The Office of Dietary Supplements provides information on supplement safety.
  • Consultation with a healthcare professional is recommended before starting any supplements.

Dose (biochemistry) Data Sources

Reference URL
Glossary https://www.alternix.com/blogs/glossary-of-terms/dose-biochemistry
Wikipedia http://en.wikipedia.org/wiki/Dose_(biochemistry)
Wikidata https://www.wikidata.org/wiki/Q473420
Knowledge Graph https://www.google.com/search?kgmid=/m/02qdgt_